Showing posts with label life. Show all posts
Showing posts with label life. Show all posts
Tuesday, December 10, 2019
Wednesday, May 6, 2015
Open Innovation in Life Science - Closing the Loop
Peer-reviewed
The first decade of the 21th century has been noted to witness a decline in the pharmaceutical innovation (Kaitin and DiMasi, 2011), with some recent signs of revival (Ward, 2014). According to the Centre for Medicines Research International in the USA, the average success rate of bringing a new drug to the market has declined, since the mid-nineties. Failure occurs predominantly in the later phases of clinical testing, which makes them even more expensive. The business witnessed only 24 new-drug approvals by the United States Food and Drug Administration during 1998 with a $27 billion Research and Development (R&D) cost. However, the industry in 2006 spent $64 billion, for only 13 new drugs, making it to the market (Kaitin and DiMasi, 2011). Some have proposed that the traditional linear model of bioinnovation, is no longer viable, concluding the need for a "fully integrated pharmaceutical networks," (FIPNets/FIPCO) or simply an "ecosystem". In this essay I explore reasons and practicalities of turning to Open Innovation. I also argue a potential enhancement in the quality of input into the earlier phases of drug production, with fungal conservation and bioprospecting as a case in point.
Wednesday, March 11, 2015
WE ARE NOT JUST ANOTHER SPECIES
لسنا كباقي الكائنات
This open letter has been e-mailed to the IUCN World Park Congress 2014.
13/7/2014
The letter/study is:
- about the necessity of collective self-awareness, unity and global governance.
An argument that the human kind is not just another species and that based on our extended phenotype we qualify as a separate kingdom of life; a sociophysiobiological kingdom with an illustration of a "Cybernetic Phylogeny";
- an expression of the human life-organisation in light of the "living-system theory" (Grier Miller cited in Umpleby, 2007), the "structure determinism" (Maturana and Valera, 1928) and the "Holistic Darwinism" (Corning, 1997).
The letter/study brings no new scientific discovery to the table, but by harnessing the existent knowledge through cybernetics, as I propose, a new multi-perspective model of the human life-organisation has simultaneously emerged.
An argument that the human kind is not just another species and that based on our extended phenotype we qualify as a separate kingdom of life; a sociophysiobiological kingdom with an illustration of a "Cybernetic Phylogeny";
- an expression of the human life-organisation in light of the "living-system theory" (Grier Miller cited in Umpleby, 2007), the "structure determinism" (Maturana and Valera, 1928) and the "Holistic Darwinism" (Corning, 1997).
The letter/study brings no new scientific discovery to the table, but by harnessing the existent knowledge through cybernetics, as I propose, a new multi-perspective model of the human life-organisation has simultaneously emerged.